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Space circumstances were preserved at 22 ± two°C and 45%–fifty% humidity, with lights set to the 12-hour gentle/darkish cycle. Animals had been fed Laboratory Diet rodent chow (Laboratory Rodent Diet no. 5001; PMI Feeds, St. Louis, MO) ad libitum right until promptly before screening. All examination ailments made use of groups of possibly 5-6

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